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Chemical Industry 2025: Adapt or die in the age of sustainability and digital disruption

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The chemical industry is currently experiencing significant changes. Decreasing demand, rising protectionist policies, changing energy dynamics, the push for zero-carbon innovations, and rapid digitalization are shaping a new era. Economic pressures are forcing companies to prioritize cost efficiency, while geopolitical tensions are reshaping global trade dynamics. At the same time, sustainability initiatives are fostering new material innovations, and AI-driven digital transformation is creating new opportunities for efficiency and growth.

HFS Research has developed a framework for next-generation manufacturing, focusing on the key pillars and enabling technologies while addressing the challenges of current operations. The chemical industry is a foundation for numerous end markets, utilizing materials to deliver products to customers in automotive, consumer care, construction, and more. This article examines the five major trends shaping the chemical industry in 2025 and discusses how customer demands and behaviors will influence interconnected areas (see Exhibit 1).

Exhibit 1: Changing dynamics of chemical manufacturers and their priorities

Source: HFS Research, 2025

Strategic refocus: Manufacturers are adjusting their strategies in response to global challenges

The global chemical industry is preparing for decreased demand due to economic challenges, inflation, and sluggish industrial activity. With major markets such as Europe and China facing difficulties, chemical companies are restructuring their portfolios, cutting costs, and divesting non-core businesses to remain competitive. BASF is at the forefront of these efforts, having sold its Styrodur® insulation business to BACHL, and its Food and Health Performance Ingredients unit to Louis Dreyfus Company in the past year. These actions align with BASF’s strategy to streamline its portfolio and concentrate on high-margin specialty chemicals.

Dow has announced $1 billion in cost-cutting measures, which include 1,500 job reductions and contracted third-party labor. Celanese is restructuring its European operations to prioritize its Engineered Materials business and enhance customer-centric innovation. In the face of economic uncertainty, chemical firms must balance cost-savings with growth investments, as only those focusing on efficiency and innovation will thrive.

Make in own country: Focus on domestic manufacturing is hindering trade between nations

Protectionist policies and the focus on ‘make in our own country’ are reshaping global chemical supply chains. Companies are localizing production, securing raw materials domestically, and lowering their reliance on imports. Countries such as the US, the European Union (EU), and China are raising tariffs, enforcing stricter trade regulations, and promoting local manufacturing to strengthen their economies.

The EU is increasing anti-dumping cases against Chinese chemical manufacturers, complicating global trade. To adapt, companies are relocating their manufacturing to the US and Europe—particularly those supporting the semiconductor industry—in response to government incentives. They are also exploring regional production hubs and partnering with local suppliers to minimize reliance on unstable trade routes. Consequently, the chemical industry is likely to become more regionalized, with an emphasis on supply chain agility and resilience.

Sustainability and circular economy: How chemical manufacturers are playing a role in the green transition

Sustainability is no longer just a compliance requirement—it’s a business imperative. To meet evolving customer expectations and net-zero targets, chemical firms are investing in low-carbon production, renewable energy, and circular economy initiatives.  For instance, LyondellBasell has committed to reducing greenhouse gas emissions by securing renewable energy sources. The company signed a 15-year agreement with Vattenfall to procure 450 gigawatt-hours of offshore wind energy annually in Germany.

Encina and BASF signed a long-term supply agreement for chemically recycled benzene, reinforcing BASF’s commitment to circular raw materials​. Dow and Freepoint Eco-Systems are building a new advanced recycling facility in Arizona, converting plastic waste into petrochemical feedstocks to promote circularity​. The race for zero-carbon innovation will separate industry leaders from laggards. Those investing in sustainable production, low-carbon feedstocks, and advanced recycling technologies will gain regulatory and market advantages as sustainability expectations continue to rise.

Supply Chain Resilience: Integrating and diversifying without disrupting production facilities

The chemical industry is currently facing supply chain volatility due to geopolitical conflicts, climate disruptions, and economic uncertainty. The war in Ukraine has driven up energy and petrochemical costs in Europe, while US-China trade tensions impact exports and raw material availability. Additionally, extreme weather events and supply chain bottlenecks complicate logistics and production. In response, chemical companies are investing in regional supply chains, digital monitoring systems, and diversified sourcing strategies to enhance their resilience and reduce dependency on single-region suppliers.

Chemical companies are increasingly adopting AI and blockchain technologies to reduce supply chain risks and improve tracking. Eastman Chemical uses GenAI for supply chain analytics and cybersecurity, improving threat detection and real-time insights. BASF’s PACIFIC app leverages blockchain for transparent Product Carbon Footprint (PCF) data exchange, boosting sustainability tracking.

These innovations transform the chemical industry by cutting costs, improving security, and ensuring traceability in a complex global market.

Digital Transformation: The move toward smart and autonomous manufacturing plants

The chemical industry rapidly embraces digital transformation through AI, predictive analytics, and blockchain. This shift enhances supply chain transparency, efficiency, and innovation while reducing costs and redefining operational efficiency. Innovative technologies such as self-driving labs are experimental platforms that fully integrate artificial intelligence, robotics, and digital technologies, leading to faster product development and a transition to a circular economy.

Celanese has introduced an AI platform that streamlines the selection of product grades and enhances the customer experience by improving communication beyond traditional phone calls and emails. The company is also leveraging AI and GenAI to integrate SAP ERP data from the various companies it has acquired in recent years. Furthermore, Celanese is developing a data lake to support advanced automation and the establishment of autonomous plants.

Eastman Chemical analyzes procurement contracts to improve negotiations and track supplier quality. Similarly, they extract insights from salesforce call notes to cross-sell, understand competitor insights, and benchmark prices for various chemical products.

AI-powered competitors will outpace chemical manufacturers that fail to digitize operations. Hence, leaders must prioritize AI adoption or risk obsolescence.

The Bottom Line: Chemical enterprises must integrate AI-driven automation, build regional supply chain resilience, and accelerate their net-zero roadmaps. This isn’t just an opportunity—it’s a survival mandate.

The chemical industry is transforming at an unprecedented pace. Economic pressures, geopolitical shifts, sustainability mandates, and digital disruption are all reshaping business operations. Trade tensions demand a flexible supply chain strategy while sustainability has become a competitive differentiator. To ensure supply chain resilience, the industry must invest in regional hubs, diversify suppliers, and embrace digital tracking technologies.

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